ViiV / Gilead
ViiV Publikationen vom CROI Kongress 2025
*denotes ViiV-supported investigator led and collaborative studies
DOLUTEGRAVIR-based regimens |
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Risk of Incident Hypertension with Common Antiretroviral Agent Combinations in the OPERA Cohort
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Immunological impact of short-term BCL-2 inhibition at ART initiation on SIV infected rhesus
macaques* |
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Drug interactions between dolutegravir (DOLUTEGRAVIR-based regimens) and escalating doses of
rifampicin (RIF): DORIS study* |
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Depression, Sleep, and Anxiety among pregnant and postpartum women using Dolutegravir and
Efavirenz* |
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Dolutegravir-based antiretroviral therapy does not reduce plasma levonorgestrel or
medroxyprogesterone acetate concentrations among contraceptive users living with HIV compared with HIV-negative
controls* |
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PK and Safety of Chronic Dolutegravir Administration in Neonates Exposed to HIV-1 (IMPAACT 2023)*
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Baseline and emergent resistance profiles in the African paediatric CHAPAS-4 trial* |
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Risk of obesity, cardiometabolic disease and MACE after switch to an integrase inhibitor in
REPRIEVE* |
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Impact of art simplification with dolutegravir and lamivudine on the HIV reservoir* |
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Switch to DOLUTEGRAVIR-based regimens/3TC vs BIC/FTC/TAF (PASO-DOBLE study): Efficacy and Weight
Changes by Predefined Subgroups* |
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Switching to DOLUTEGRAVIR-based regimens/3TC vs. BIC/FTC/TAF and Steatotic Liver Disease: A
Sub-study of PASODOBLE Trial* |
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Effectiveness and inflammatory markers after 144 weeks of switch to DOLUTEGRAVIR-based
regimens/3TC in a randomized trial* |
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Rapid clearance of the inducible HIV-1 reservoir after initiation of antiretroviral therapy*
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Changes in body composition in people with HIV switching to DOLUTEGRAVIR-based regimens/3TC or
BIC/TAF/FTC* |
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CABOTEGRAVIR + RILPIVIRINE Long-acting for treatment |
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Long-term CAB+RPV LA Effectiveness in Virologically Suppressed Individuals in the OPERA Cohort
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Clinical Outcomes Among Virologically Suppressed Women Receiving CAB+RPV LA in the OPERA Cohort
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Outcomes on Cabotegravir + Rilpivirine in Suppressed People with HIV (PWH) in TRIO Health US
Cohort |
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Decreasing oral induction duration in support of LAI ART use with hardly-reached populations*
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At Home CAB/RPV Provides Novel Approach to Achieve Viral Suppression in Adherence Challenged PWH*
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Safety and Pharmacokinetics of long-acting Cabotegravir and Rilpivirine in children between
20-40kgs* |
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CABOTEGRAVIR Long-acting for prevention |
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PILLAR Month 12 clinical results: Zero HIV acquisition and high persistence with CAB LA for PrEP
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No increased risk for hypertension with CAB-LA compared to TDF/FTC for PrEP: results from HPTN
084* |
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Performance of HIV RNA screening in the context of long-acting injectable cabotegravir in HPTN
084* |
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High incidence of curable sexually transmitted infections in HPTN 084: a tertiary analysis*
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PrEP Choices Among Sexual and Gender Minorities in Brazil: the ImPrEP CAB-LA Study* |
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Depression and Suicide Risk Among Sexual and Gender Minorities: Insights from the ImPrEP CAB
Brasil* |
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Patterns of First Choice, Switching, and Discontinuation of Oral and Injectable PrEP Among
Adolescents from Sexual and Gender Minorities in Brazil* |
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Acceptability of long-acting cabotegravir among pregnant and lactating people in South Africa*
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Impact of rapid long-acting prep scale-up among MSM: closing the unmet needs and towards ending
HIV* |
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Response to HIV Treatment After Long-Acting Cabotegravir Pre-exposure Prophylaxis in HPTN 083*
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Expanding the PrEP method market: Early insights from offering oral PrEP, PrEP ring, and
injectable CABOTEGRAVIR Long-acting for prevention for HIV prevention across five countries in Africa* |
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Dynamic Choice HIV Prevention in the context of Injectable Cabotegravir (CAB-LA): a model-based
cost-effectiveness analysis* |
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ImPrEP CAB Brasil: Enhancing PrEP Coverage with CAB-LA in Young Key Populations* |
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Estimation of prevention-effective CAB-LA concentrations among MSM/TGW in HPTN 083* |
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Use of DNA profiling to resolve discrepant HIV tests in the setting of injectable cabotegravir
PrEP* |
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Fostemsavir |
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Characteristics and Treatment Outcomes of People With HIV Prescribed Fostemsavir in The Trio
Cohort |
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Pipeline |
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Proof-of-Concept Trial of VH4524184 (VH-184), a Third-Generation Integrase Strand Transfer
Inhibitor |
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Proof-of-Concept Trial of Oral VH4011499 (VH-499), a New HIV-1 Capsid Inhibitor |
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VH3810109 (N6LS) Efficacy and Safety in Adults Who Are Virologically Suppressed: The EMBRACE
Study |
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Pre-clinical evaluation of effector function-enhanced variants of N6 bnAb |
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Other HIV-related data |
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Temsavir treatment improves the recognition of HIV-1 infected cells by broadly neutralizing
antibodies (bnAbs) |
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Cancer incidence in women with HIV in Europe and Australia: a combined D:A:D and RESPOND cohort
analysis |
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Determinants of steatotic liver disease among people with HIV in Europe and Australia |
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Hospitalization Incidence Among Young Children Living with HIV in the Western Cape, South Africa
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People with HIV at high cardiovascular risk were undertreated with statins* |
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Increasing Methamphetamine Use and Group Sex Observed in MSM with Acute HIV Infection in Bangkok*
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Statin Effect Heterogeneity on Plaque Volume & Composition in the REPRIEVE Mechanistic
Substudy* |
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Frailty is Associated with Higher MACE Incidence but Does Not Appear to Modify Pitavastatin
Effects* |
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No Evidence of a Detrimental Effect of Pitavastatin on Neurocognitive Function Among People with
HIV* |
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Plaque, Inflammation, Subclinical Myocardial Injury and MACE in the REPRIEVE Mechanistic
Substudy* |
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Prognostic Factors of Physical Function Decline in the PREPARE Study* |
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Time-updated win ratio aligns with primary REPRIEVE findings and suggests early pitavastatin
benefit* |
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Heart Failure Risk and Events in People With HIV in the REPRIEVE Trial* |
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Cognitive Trajectories 1 year before and after COVID-19 in an AHI cohort* |
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ART Exposure and Accelerated Aging in PLHIV: Insights from Proteomic and Methylation Clocks*
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Modulation of CCR5 Expression is Critical for the Maintenance of HIV Control and Reservoir Size*
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Genetic regulation of immune responses to CMV in spontaneous HIV controllers* |
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Delayed HIV-1 rebound correlates with enhanced CD8 T Cell activation in human trials* |
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Virulent HIV-1B: Clinical Challenges and Proteomic Insights* |
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Distinct Metabolic Perturbations Link Liver Steatosis and Incident CVD in Lean but Not Obese
PLHIV* |
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Brain volume normalization after 96 weeks of ART started during acute HIV infection* |
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People with HIV exhibit structural brain changes following infection with SARS-COV-2* |
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Mitochondrial Gene Variants in VARS2 Influence HIV Reservoir and T Cells in European HIV
Controllers* |
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Multi-omics Clustering Reveals Distinct HIV Reservoir Profiles in the 2000HIV Cohort* |
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Heterogeneity of PD-1 expression in People Living with HIV and its relationship with host and
viral-related factors* |
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Residual HIV viremia: association with reservoir, functional immunology and systemic
inflammation* |
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Neuronal Injury in a Subset of Individuals during Acute HIV Infection and After Immediate
Treatment* |
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Early HIV-1 genetic diversity includes CTL and drug resistance mutations* |
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RV550: The effects of IL-15 super-agonist N-803 with ART in acute infection on T and NK cells*
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RV550: Safety and virological outcomes in blood and lymph nodes of N-803 with ART in acute
infection* |
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Sex-based differences and genetic regulation of cytokine responses in people living with HIV*
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Females With HIV Favor Interferon Responses Over Inflammation Upon TLR7 Activation* |
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Maximizing Benefits to Participants in Analytic Treatment Interruption Studies with bnAb
infusions* |
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Neutralization sensitivity of viral reservoir envelopes to broadly neutralizing antibodies
VRC07-523LS and PGDM1400LS* |